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From J. M. Grandclément   [May 1874]

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Summary

He was chagrined to read in Descent CD’s statement that smallpox vaccine has saved thousands of lives. He has found no scientific reason to believe in the prophylactic effect of the vaccine. In epidemic of 1870–1, smallpox killed more vaccinated persons than were killed by cholera, against which there is no vaccine, in 1853–4. Cites the difficulties in arriving at a conclusive proof of vaccine’s effectiveness.

Author:  Joseph Marie Grandclément
Addressee:  Charles Robert Darwin
Date:  [May 1874]
Classmark:  DAR 165: 87
Letter no:  DCP-LETT-9436

From W. W. Keen   [May–June? 1874]

Summary

CD’s theory has his qualified support.

He suggests the inheritance of syphilis as an example of sexual selection.

Gives an example of inherited expression in his wife’s and daughter’s frowns.

Author:  William Williams Keen
Addressee:  Charles Robert Darwin
Date:  [May–June? 1874]
Classmark:  DAR 169: 2
Letter no:  DCP-LETT-9437